FCRN/FCGRT Antibody (CL3640)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-61627

Novus Biologicals, part of Bio-Techne
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NBP2-61627-25ul
NBP2-61627
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL3640

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all FCRN Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: LTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKS

Epitope

GQGDFGPNSD

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for FCRN/FCGRT Antibody (CL3640)

Western Blot: FCRN/FCGRT Antibody (CL3640) [NBP2-61627]

Western Blot: FCRN/FCGRT Antibody (CL3640) [NBP2-61627]

Western Blot: FCRN/FCGRT Antibody (CL3640) [NBP2-61627] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10
Lane 2: Human cell line THP-1
Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody (CL3640) [NBP2-61627]

Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody (CL3640) [NBP2-61627]

Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody (CL3640) [NBP2-61627] - Staining of human cerebral cortex shows absence of immunoreactivity (negative control).
Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody (CL3640) [NBP2-61627]

Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody (CL3640) [NBP2-61627]

Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody (CL3640) [NBP2-61627] - Staining of human lymph node shows strong positivity in a subset of lymphoid cells.
View 3 more images

Applications for FCRN/FCGRT Antibody (CL3640)

Application
Recommended Usage

Immunohistochemistry

1:5000 - 1:10000

Immunohistochemistry-Paraffin

1:5000 - 1:10000

Western Blot

1 ug/ml
Application Notes
IHC-Paraffin HIER pH6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FCRN

The FCGRT gene encodes a 365 amino acid long, 39 kDA IgG receptor FcRn large subunit p51 protein that transfers immunoglobulin G antibodies across the placenta from mother to fetus, as well as functions to protect the antibody from degradation. FCGRT interacts with genes CA6, ELANE, AZGP1, B2M, and ALB. It has been linked to diseases such as: lupus, nephritis, leukemia, arthritis, immunodeficiency, epidermolysis bullosa acquisita, persistent fetal circulation syndrome, and pemphigus.

Long Name

Neonatal Fc Receptor

Alternate Names

FCGRT

Gene Symbol

FCGRT

Additional FCRN Products

Product Documents for FCRN/FCGRT Antibody (CL3640)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for FCRN/FCGRT Antibody (CL3640)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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