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FDFT1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-32147

Novus Biologicals, part of Bio-Techne
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NBP1-32147

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (92%), Mouse (90%), Porcine (93%), Primate (98%), Rhesus Macaque (99%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for FDFT1 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human FDFT1. The exact sequence is proprietary.

Reactivity Notes

Chimpanzee (98%), Rat (88%).

Localization

Endoplasmic reticulum membrane, Multi-pass membrane protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

48 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for FDFT1 Antibody

Immunohistochemistry-Paraffin: FDFT1 Antibody [NBP1-32147]

Immunohistochemistry-Paraffin: FDFT1 Antibody [NBP1-32147]

Immunohistochemistry-Paraffin: FDFT1 Antibody [NBP1-32147] - Paraffin-embedded liver, using antibody at 1:100 dilution.
FDFT1 Antibody

Western Blot: FDFT1 Antibody [NBP1-32147] -

Western Blot: FDFT1 Antibody [NBP1-32147] - Whole cell extract (30 ug) was separated by 12% SDS-PAGE, and the membrane was blotted with FDFT1 antibody [N2C3] (NBP1-32147) diluted at 1:1500. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Applications for FDFT1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: FDFT1

This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.

Long Name

Squalene synthase

Alternate Names

EC 2.5.1.21, SQS, SS

Gene Symbol

FDFT1

Additional FDFT1 Products

Product Documents for FDFT1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for FDFT1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.