Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI2B6

Concentration

1 mg/ml

View all FGF-BP Antibodies »

Product Specifications

Immunogen

Human recombinant protein fragment corresponding to amino acids 24-234 of human FGFBP1(NP_005121) produced in E.coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

26.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for FGF-BP Antibody (OTI2B6)

Western Blot: FGF-BP Antibody (OTI2B6) [NBP2-45643]

Western Blot: FGF-BP Antibody (OTI2B6) [NBP2-45643]

Western Blot: FGF-BP Antibody (OTI2B6) [NBP2-45643] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FGF-BP.
Immunohistochemistry-Paraffin: FGF-BP Antibody (OTI2B6) [NBP2-45643]

Immunohistochemistry-Paraffin: FGF-BP Antibody (OTI2B6) [NBP2-45643]

Immunohistochemistry-Paraffin: FGF-BP Antibody (OTI2B6) [NBP2-45643] - Analysis of Human prostate tissue. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0)
Immunohistochemistry-Paraffin: FGF-BP Antibody (OTI2B6) [NBP2-45643]

Immunohistochemistry-Paraffin: FGF-BP Antibody (OTI2B6) [NBP2-45643]

Immunohistochemistry-Paraffin: FGF-BP Antibody (OTI2B6) [NBP2-45643] - Analysis of Human Ovary tissue. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0)

Applications for FGF-BP Antibody (OTI2B6)

Application
Recommended Usage

Immunohistochemistry

1:150

Western Blot

1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: FGF-BP

FGFBP1, also known as Fibroblast growth factor-binding protein 1, is a 234 amino acid protein that is approximately 26 kDa, acts as a carrier protein that release fibroblast-binding factors (FGFs) enhancing its mitogenic activity and can be found secreted, in extracellular space and cell membrane. This protein is currently being studied for research on the following diseases and disorders: squamous cell carcinoma, breast cancer, colon cancer, pancreatitis, hypertension, narcolepsy, ataxia, prostatitis, and peritonitis. FGFBP1 has also been shown to have interactions with FGF2, FIBP, NRP2, UBQLN4 and HSPG2 in pathways such as the positive regulation of fibroblast growth factor receptor signaling pathway, positive and negative regulation of cell proliferation, cell-cell signaling and signal transduction.

Long Name

Fibroblast Growth Factor Binding Protein

Alternate Names

FGF-BP1, FGFBP, FGFBP-1, FGFBP1, HBp17

Gene Symbol

FGFBP1

Additional FGF-BP Products

Product Documents for FGF-BP Antibody (OTI2B6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for FGF-BP Antibody (OTI2B6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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