FGFR1 [p Tyr651, p Tyr652] Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-24462

Novus Biologicals, part of Bio-Techne
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NBP2-24462
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human, Mouse

Predicted:

Chicken (100%), Mouse (100%), Rat (100%), Zebrafish (100%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all FGFR1 Antibodies »

Product Specifications

Immunogen

Amino acids RDIHHIDYYKKTTN of human FGFR1 protein containing phosphorylated tyrosine residues at positions 651 and 652 were used as the immunogen for this antibody.

Modification

p Tyr651, p Tyr652

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FGFR1 [p Tyr651, p Tyr652] Antibody

Western Blot: FGFR1 [p Tyr651, p Tyr652] Antibody [NBP2-24462]

Western Blot: FGFR1 [p Tyr651, p Tyr652] Antibody [NBP2-24462]

Western Blot: FGF R1 [p Tyr651, p Tyr652] Antibody [NBP2-24462] - Analysis of FGFR phosphoin recombinant fusion protein containing 1) phosphorylated tyrosine residues at positions 651 and 652 and 2) unphosphorylated tyrosine residues at positions 651 and 652, using FGFR phospho antibody at 0.002 ug/ml. Goat anti-rabbit IgG HRP secondary antibody and PicoTect ECL substrate solution were used for this test.
Immunohistochemistry-Paraffin: FGFR1 [p Tyr651, p Tyr652] Antibody [NBP2-24462]

Immunohistochemistry-Paraffin: FGFR1 [p Tyr651, p Tyr652] Antibody [NBP2-24462]

Immunohistochemistry-Paraffin: FGF R1 [p Tyr651, p Tyr652] Antibody [NBP2-24462] - Analysis of FGFR1 phospho in formalin-fixed, paraffin-embedded human breast tumor tissue using an isotype control antibody (top left) and FGFR1 phospho antibody (bottom left, right) at 5 ug/ml.

Applications for FGFR1 [p Tyr651, p Tyr652] Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

0.1-1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

0.1 ml PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: FGFR1

FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGF R1 through 5. FGF Rs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGF R1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGF R5 does not. Multiple forms of FGF R1, 2, and 3 are generated by alternative splicing

Long Name

Fibroblast Growth Factor Receptor 1

Alternate Names

CD331, FGF R1, Flt-2

Gene Symbol

FGFR1

UniProt

P11362

Additional FGFR1 Products

Product Documents for FGFR1 [p Tyr651, p Tyr652] Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for FGFR1 [p Tyr651, p Tyr652] Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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