FGFR5/FGFRL1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-31461

Novus Biologicals, part of Bio-Techne
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NBP1-31461
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all FGFR5/FGFRL1 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human FGFR5/FGFRL1. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (86%), Rat (86%), Bovine (89%).

Localization

Membrane, Single-pass type I membrane protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for FGFR5/FGFRL1 Antibody

Western Blot: FGFR5/FGFRL1 Antibody [NBP1-31461]

Western Blot: FGFR5/FGFRL1 Antibody [NBP1-31461]

Western Blot: FGFR5/FGFRL1 Antibody [NBP1-31461] - Non-transfected (-) and transfected (+) 293T whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with FGFR5 antibody diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
Immunohistochemistry-Paraffin: FGFR5/FGFRL1 Antibody [NBP1-31461]

Immunohistochemistry-Paraffin: FGFR5/FGFRL1 Antibody [NBP1-31461]

Immunohistochemistry-Paraffin: FGF R5/FGFRL1 Antibody [NBP1-31461] - Paraffin-embedded Oral CA Cal27 xenograft, using antibody at 1:100 dilution.
Western Blot: FGFR5/FGFRL1 Antibody [NBP1-31461]

Western Blot: FGFR5/FGFRL1 Antibody [NBP1-31461]

Western Blot: FGFR5/FGFRL1 Antibody [NBP1-31461] - HepG2 whole cell and membrane extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with FGFR5 antibody diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.

Applications for FGFR5/FGFRL1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: FGFR5/FGFRL1

The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq]

Long Name

Fibroblast Growth Factor Receptor-like 1

Alternate Names

FGF R5, FGFRL1

Entrez Gene IDs

53834 (Human)

Gene Symbol

FGFRL1

UniProt

Q8N441

Additional FGFR5/FGFRL1 Products

Product Documents for FGFR5/FGFRL1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for FGFR5/FGFRL1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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