Fibrinogen gamma chain Antibody (1F2)

Novus Biologicals, part of Bio-Techne | Catalog # H00002266-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Proximity Ligation Assay, Sandwich ELISA, Western Blot

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 1F2

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Fibrinogen gamma chain Antibodies »

Product Specifications

Immunogen

FGG (AAH07044, 31 a.a. ~ 130 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. RDNCCILDERFGSYCPTTCGIADFLSTYQTKVDKDLQSLEDILHQVENKTSEVKQLIKAIQLTYNPDESSKPNMIDAATLKSRKMLEEIMKYEASILTHD

Specificity

FGG - fibrinogen gamma chain

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for Fibrinogen gamma chain Antibody (1F2)

Western Blot: Fibrinogen gamma chain Antibody (1F2) [H00002266-M01]

Western Blot: Fibrinogen gamma chain Antibody (1F2) [H00002266-M01]

Western Blot: Fibrinogen gamma chain Antibody (1F2) [H00002266-M01] - FGG monoclonal antibody (M01), clone 1F2 Analysis of FGG expression in Hela S3 NE.
Immunohistochemistry-Paraffin: Fibrinogen gamma chain Antibody (1F2) [H00002266-M01]

Immunohistochemistry-Paraffin: Fibrinogen gamma chain Antibody (1F2) [H00002266-M01]

Immunohistochemistry-Paraffin: Fibrinogen gamma chain Antibody (1F2) [H00002266-M01] - Analysis of monoclonal antibody to FGG on formalin-fixed paraffin-embedded human hepatocellular carcinoma tissue. Antibody concentration 1 ug/ml.
Proximity Ligation Assay: Fibrinogen gamma chain Antibody (1F2) [H00002266-M01]

Proximity Ligation Assay: Fibrinogen gamma chain Antibody (1F2) [H00002266-M01]

Proximity Ligation Assay: Fibrinogen gamma chain Antibody (1F2) [H00002266-M01] - Analysis of protein-protein interactions between ICAM1 and FGG. HeLa cells were stained with anti-ICAM1 rabbit purified polyclonal 1:1200 and anti-FGG mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).
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Applications for Fibrinogen gamma chain Antibody (1F2)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IHC-P and ELISA.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Fibrinogen gamma chain

The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.

Alternate Names

fibrinogen gamma chain, fibrinogen, gamma polypeptide

Entrez Gene IDs

2266 (Human)

Gene Symbol

FGG

OMIM

134850 (Human)

UniProt

AAH07044 (Human)

Additional Fibrinogen gamma chain Products

Product Documents for Fibrinogen gamma chain Antibody (1F2)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Fibrinogen gamma chain Antibody (1F2)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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