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Ficolin-3 Antibody (FCN334) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-41283

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Immunoprecipitation, Sandwich ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # FCN334

Format

BSA Free

Concentration

1.0 mg/ml

Product Summary for Ficolin-3 Antibody (FCN334) - BSA Free

Immunogen

Recombinant human H-ficolin

Specificity

Reacts specifically with H-ficolin. No cross-reaction has been observed with L- or M-ficolin.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Applications for Ficolin-3 Antibody (FCN334) - BSA Free

Application
Recommended Usage

ELISA

1:32000
Application Notes
ELISA: NBP1-41283 reacts with recombinant H-ficolin coated directly onto the microtiter well. A sandwich ELISA for H-ficolin uses NBP1-41283 for both capture and detection. (1)
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10mM Phosphate (pH 7.4) and 0.5M NaCl

Format

BSA Free

Preservative

0.9% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Ficolin-3

Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified. [provided by RefSeq]

Long Name

Ficolin [Collagen/Fibrinogen Domain Containing] 3

Alternate Names

FCN3, FCNH, Ficolin3, H-Ficolin, HAKA1

Gene Symbol

FCN3

Additional Ficolin-3 Products

Product Documents for Ficolin-3 Antibody (FCN334) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Ficolin-3 Antibody (FCN334) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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