Filamin A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-58814

Novus Biologicals, part of Bio-Techne
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NB100-58814
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Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all Filamin A Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 2597 and 2647 of human Filamin A using the numbering given in entry NP_001447.1 (GeneID 2316).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Filamin A Antibody

Western Blot: Filamin A Antibody [NB100-58814]

Western Blot: Filamin A Antibody [NB100-58814]

Western Blot: Filamin A Antibody [NB100-58814] - Detection of Human and Mouse Filamin A on HeLa whole cell lysate using NB100-58814. Filamin A was also immunoprecipitated by rabbit anti-Filamin A antibody NB100-58813.
Immunohistochemistry-Paraffin: Filamin A Antibody [NB100-58814]

Immunohistochemistry-Paraffin: Filamin A Antibody [NB100-58814]

Immunohistochemistry-Paraffin: Filamin A Antibody [NB100-58814] - Section of human colon carcinoma. Antibody: Affinity purified rabbit anti-Filamin A used at a dilution of 1:1,000 (0.2ug/ml). Detection: DAB

Applications for Filamin A Antibody

Application
Recommended Usage

Immunohistochemistry

1:500-1:2000

Immunohistochemistry-Paraffin

1:500-1:2000

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000
Application Notes
Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Filamin A

Actin-binding protein, or filamin, is a 280-kD protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and participates in the anchoring of membrane proteins for the actin cytoskeleton. Remodeling of the cytoskeleton is central to the modulation of cell shape and migration. Filamin A, encoded by the FLNA gene, is a widely expressed protein that regulates reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and second messengers.[supplied by OMIM]

Long Name

Filamin-A

Alternate Names

ABP-280, Alpha-filamin, Filamin-1, FLN, FLN-A, FLN1, FLNA, Non-muscle filamin

Entrez Gene IDs

2316 (Human); 192176 (Mouse)

Gene Symbol

FLNA

UniProt

P21333 (Human)

Additional Filamin A Products

Product Documents for Filamin A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Filamin A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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