RELM alpha, also known as found in inflammatory zone (FIZZ1) belongs to the RELM1/FIZZ family of cysteine-rich secretory proteins and shares homology with resistin. It is abundantly expressed in white adipose tissue but not in preadipocytes, nor 3T3-L1 adipocytes. RELM alpha expression is also detected in bronchial epithelium and type II pneumocytes. RELM beta (resistin-like molecule beta/FIZZ2) is a cysteine-rich protein expressed specifically in the intestine. It is highly homologous to resistin and RELM alpha. RELM beta and resistin contain eleven cysteines with identical spacing which mediate formation of disulfide-linked homodimers. They further associate into trimers and hexamers.

Long Name

Found in Inflammatory Zone 1/Resistin-like Molecule alpha

Alternate Names

RELM alpha, RETNLA, RETNLB

Gene Symbol

RETNLA

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Product Specific Notices for FIZZ1/RELM alpha Antibody (RM0313-9A39) [Janelia Fluor® 635]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FIZZ1/RELM alpha Antibody (RM0313-9A39) [Janelia Fluor® 635]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-12440JF635

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Background: FIZZ1/RELM alpha