FMO1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86412

Novus Biologicals, part of Bio-Techne
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NBP1-86412-25ul
NBP1-86412
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all FMO1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LPTPIVTWLMERKINNWLNHANYGLIPEDRTQLKEFVLNDELPGRIITGKVFIRPSIKEVKENSVIFNNTSKEEPIDIIVFATGYTFAFPFLDESVVKVEDG

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (85%), Rat (80%). Human reactivity reported in scientific literature (PMID: 23952781).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FMO1 Antibody

Immunohistochemistry-Paraffin: FMO1 Antibody [NBP1-86412]

Immunohistochemistry-Paraffin: FMO1 Antibody [NBP1-86412]

Immunohistochemistry-Paraffin: FMO1 Antibody [NBP1-86412] - Staining of human liver shows moderate cytoplasmic positivity in hepatocytes.
Immunohistochemistry: FMO1 Antibody [NBP1-86412]

Immunohistochemistry: FMO1 Antibody [NBP1-86412]

Immunohistochemistry: FMO1 Antibody [NBP1-86412] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: FMO1 Antibody [NBP1-86412]

Immunohistochemistry-Paraffin: FMO1 Antibody [NBP1-86412]

Immunohistochemistry-Paraffin: FMO1 Antibody [NBP1-86412] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells.
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Applications for FMO1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
IHC reported in scientific literature (PMID: 23952781). For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FMO1

Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase andis subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidationcapacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenasesare NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs,pesticides, and xenobiotics. (provided by RefSeq)

Alternate Names

dimethylaniline monooxygenase [N-oxide-forming] 1, Dimethylaniline oxidase 1, EC 1.14.13.8, Fetal hepatic flavin-containing monooxygenase 1, flavin containing monooxygenase 1, Flavin-containing monooxygenase 1 (fetal liver), FMO 1

Gene Symbol

FMO1

Additional FMO1 Products

Product Documents for FMO1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FMO1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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