FMO2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-33318

Novus Biologicals, part of Bio-Techne
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NBP1-33318
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Primate (99%), Rhesus Macaque (96%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all FMO2 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human FMO2. The exact sequence is proprietary.

Reactivity Notes

Chimpanzee (99%), Bovine (81%), Mouse (83%), Rat (82%), Rabbit (84%).

Localization

Microsome membrane, Endoplasmic reticulum membrane

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

54 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for FMO2 Antibody

Western Blot: FMO2 Antibody [NBP1-33318]

Western Blot: FMO2 Antibody [NBP1-33318]

Western Blot: FMO2 Antibody [NBP1-33318] - Sample (30 ug of whole cell lysate) A: Hep G2 10% SDS PAGE; antibody diluted at 1:1000.
Immunohistochemistry-Paraffin: FMO2 Antibody [NBP1-33318]

Immunohistochemistry-Paraffin: FMO2 Antibody [NBP1-33318]

Immunohistochemistry-Paraffin: FMO2 Antibody [NBP1-33318] - Paraffin-embedded A549 xenograft, using antibody at 1:500 dilution.

Applications for FMO2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: FMO2

The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1.

Alternate Names

dimethylaniline monooxygenase [N-oxide-forming] 2, Dimethylaniline oxidase 2, EC 1.14.13.8, flavin containing monooxygenase 2, flavin containing monooxygenase 2 (non-functional), FLJ40826, FMO 1B1, FMO 2, FMO, pulmonary, FMO1B1, Pulmonary flavin-containing monooxygenase 2

Gene Symbol

FMO2

Additional FMO2 Products

Product Documents for FMO2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for FMO2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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