FMRP Antibody (4G9) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-42567

Novus Biologicals, part of Bio-Techne
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NBP1-42567
NBP1-42567-0.025ml
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 4G9

Format

BSA Free

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all FMRP Antibodies »

Product Specifications

Immunogen

Purified recombinant fragment of human FMRP expressed in E. Coli.

Reactivity Notes

Human.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

71 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for FMRP Antibody (4G9) - BSA Free

Western Blot: FMRP Antibody (4G9)BSA Free [NBP1-42567]

Western Blot: FMRP Antibody (4G9)BSA Free [NBP1-42567]

Western Blot: FMRP Antibody (4G9) [NBP1-42567] - analysis using FMR1 mouse mAb against Jurkat (1) and K562 (2) cell lysate.
Immunocytochemistry/ Immunofluorescence: FMRP Antibody (4G9) - BSA Free [NBP1-42567]

Immunocytochemistry/ Immunofluorescence: FMRP Antibody (4G9) - BSA Free [NBP1-42567]

Immunocytochemistry/Immunofluorescence: FMRP Antibody (4G9) [NBP1-42567] - Immunofluorescence analysis of NIH/3T3 cells using FMR1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Immunohistochemistry-Paraffin: FMRP Antibody (4G9) - BSA Free [NBP1-42567]

Immunohistochemistry-Paraffin: FMRP Antibody (4G9) - BSA Free [NBP1-42567]

Immunohistochemistry-Paraffin: FMRP Antibody (4G9) [NBP1-42567] - analysis of paraffin-embedded human brain tissues, showing cytoplasmic localization with DAB staining using FMR1 mouse mAb.

Applications for FMRP Antibody (4G9) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Immunocytochemistry/ Immunofluorescence

1:200-1:1000

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:200-1:1000

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Ascites

Format

BSA Free

Preservative

0.03% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FMRP

Fragile X syndrome is the most common inherited form of mental retardation. It is caused by loss of FMR1 gene activity due to either lack of expression or expression of a mutant form of the protein. In mammals, FMR1 is a member of a small protein family that consists of FMR1, FXR1, and FXR2. All three members bind RNA and contain sequence motifs that are commonly found in RNA-binding proteins, including two KH domains and an RGG box.The Drosophila genome contains a single gene homologous to the FXR family. dFMR1 is subjected to transcriptional and posttranscriptional regulation during development and it homomerizes, like its human counterpart. dFMR1 profile of expression recapitulates that of the human FXR protein family: it is highly enriched in muscles, in central nervous system and in gonads. In the larval brain, anti-dFMR1 also recognizes mushroom bodies, a centre that mediates learning and memory. These features make the fly an ideal system to analyze the role of the FXR family and to identify genes in the FMRP pathway.

Alternate Names

FMRPFRAXAPOF, fragile X mental retardation 1, fragile X mental retardation 1 protein, MGC87458, POF1, premature ovarian failure 1, Protein FMR-1

Gene Symbol

FMR1

Additional FMRP Products

Product Documents for FMRP Antibody (4G9) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for FMRP Antibody (4G9) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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