FMRP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-20918

Novus Biologicals, part of Bio-Techne
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NBP1-20918
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Canine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all FMRP Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-RTGKDRNQKKEKPD corresponding to internal region (near C-Terminus) according to NP_002015.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for FMRP Antibody

Western Blot: FMRP Antibody [NBP1-20918]

Western Blot: FMRP Antibody [NBP1-20918]

Western Blot: FMRP Antibody [NBP1-20918] - (0.1ug/ml) staining of KELLY cell lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for FMRP Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

2.5 ug/ml

Peptide ELISA

Detection limit 1:128000

Western Blot

0.1 - 0.3 ug/ml
Application Notes
WB: Approx. 80 kDa band observed in KELLY lysate is reproted in scientific literature (PMID: 8789445).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: FMRP

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1).

Alternate Names

FMRPFRAXAPOF, fragile X mental retardation 1, fragile X mental retardation 1 protein, MGC87458, POF1, premature ovarian failure 1, Protein FMR-1

Entrez Gene IDs

2332 (Human); 14265 (Mouse); 24948 (Rat)

Gene Symbol

FMR1

UniProt

Q06787 (Human)

Additional FMRP Products

Product Documents for FMRP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FMRP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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