FNBP1L Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76846

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all FNBP1L Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of the human TOCA-1. The immunogen is located within amino acids 40 - 90 of TOCA-1. Amino Acid Squence: CPKRSSKDEEPRFTS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FNBP1L Antibody - BSA Free

Western Blot: FNBP1L AntibodyBSA Free [NBP1-76846]

Western Blot: FNBP1L AntibodyBSA Free [NBP1-76846]

Western Blot: FNBP1L Antibody [NBP1-76846] - Human brain tissue lysate in (A) the absence and (B) the presence of blocking peptide with FNBP1L antibody at 0.5 ug/mL.
Immunocytochemistry/ Immunofluorescence: FNBP1L Antibody - BSA Free [NBP1-76846]

Immunocytochemistry/ Immunofluorescence: FNBP1L Antibody - BSA Free [NBP1-76846]

Immunocytochemistry/Immunofluorescence: FNBP1L Antibody [NBP1-76846] - Human Brain cells.
Immunohistochemistry-Paraffin: FNBP1L Antibody - BSA Free [NBP1-76846]

Immunohistochemistry-Paraffin: FNBP1L Antibody - BSA Free [NBP1-76846]

Immunohistochemistry-Paraffin: FNBP1L Antibody [NBP1-76846] - Human brain tissue using FNBP1L antibody at 2.5 ug/ml.

Applications for FNBP1L Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

0.5 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FNBP1L

Actin reorganization is important for the regulation of neuronal morphology. A protein involved in this process, the transducer of cdc42-dependent actin assembly 1 (TOCA-1) protein, a member of the evolutionarily conserved pombe CDC15 homology (PCH) protein family, is an essential component of the Cdc42 pathway. TOCA-1 binds both N-WASP and Cdc42 and is essential for Cdc42- and PIP2-induced actin polymerization, suggesting that TOCA-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex. Decreased expression of TOCA-1 significantly enhances neurite elongation in PC-12 cells; its overexpression in the same cells suppresses neurite elongation. It has been suggested that TOCA-1 negatively regulates axon branching by regulating membrane trafficking by regulating membrane trafficking through the F-BAR/EFC domain. Multiple isoforms of TOCA-1 are known to exist.

Alternate Names

C1orf39, chromosome 1 open reading frame 39, FLJ20275, formin binding protein 1-like, formin-binding protein 1-like, toca-1, TOCA1Transducer of Cdc42-dependent actin assembly protein 1, transducer of Cdc42-dependent actin assembly 1

Gene Symbol

FNBP1L

UniProt

NP_001020119 (Human)

Additional FNBP1L Products

Product Documents for FNBP1L Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FNBP1L Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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