FosB/G0S3 Antibody (83B1138) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56530

Novus Biologicals, part of Bio-Techne
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NB100-56530
NB100-56530SS
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Azide Free
NBP2-33219
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 83B1138

Format

BSA Free

Concentration

1.0 mg/ml

View all FosB/G0S3 Antibodies »

Product Summary for FosB/G0S3 Antibody (83B1138) - BSA Free

Immunogen

This antibody was generated by immunizing mice with a synthetic peptide corresponding to amino acids 2-15 of human FosB.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for FosB/G0S3 Antibody (83B1138) - BSA Free

Western Blot: FosB/G0S3 Antibody (83B1138)BSA Free [NB100-56530]

Western Blot: FosB/G0S3 Antibody (83B1138)BSA Free [NB100-56530]

Western Blot: FosB/G0S3 Antibody (83B1138) [NB100-56530] - Analysis of FosB in HeLa cell lysate where bands are observed at ~38 kDa representing FosB and at ~35 kDa representing delta FosB.

Applications for FosB/G0S3 Antibody (83B1138) - BSA Free

Application
Recommended Usage

Western Blot

2 ug/mL
Application Notes
In WB of HeLa cells, a 46 kDa band is observed.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FosB/G0S3

The v-Fos oncogene was initially identified as the transforming gene of two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a 62 kDa nuclear phosphoprotein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo and heterodimers, which bind to specific DNA TPA response elements (TREs), c-Fos proteins are only active as heterodimers with members of the Jun gene family. Murine FosB encodes a nuclear protein of 338 amino acids which has 70% homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and FosB include Fra-1 and Fra-2 genes.

Long Name

FBJ Murine Osteosarcoma Viral Oncogene Homolog B

Alternate Names

G0S3

Entrez Gene IDs

2354 (Human)

Gene Symbol

FOSB

UniProt

P53539

Additional FosB/G0S3 Products

Product Documents for FosB/G0S3 Antibody (83B1138) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FosB/G0S3 Antibody (83B1138) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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