FoxP2 Antibody (CL5310)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-61412

Novus Biologicals, part of Bio-Techne
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NBP2-61412
NBP2-61412-25ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Rat (97%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL5310

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all FoxP2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: AQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHS

Epitope

PQAGLSPAEIQQLWK

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for FoxP2 Antibody (CL5310)

Immunocytochemistry/ Immunofluorescence: FoxP2 Antibody (CL5310) [NBP2-61412]

Immunocytochemistry/ Immunofluorescence: FoxP2 Antibody (CL5310) [NBP2-61412]

Immunocytochemistry/Immunofluorescence: FoxP2 Antibody (CL5310) [NBP2-61412] - Staining of RH-30 cells using the Anti-FOXP2 monoclonal antibody, showing specific staining in the nucleoplasm in green. Microtubule and nuclear probes are visualized in red and blue, respectively (where available). Antibody staining is shown in green.
Immunohistochemistry-Paraffin: FoxP2 Antibody (CL5310) [NBP2-61412]

Immunohistochemistry-Paraffin: FoxP2 Antibody (CL5310) [NBP2-61412]

Immunohistochemistry-Paraffin: FoxP2 Antibody (CL5310) [NBP2-61412] - Staining of mouse cerebral cortex shows strong nuclear immunoreactivity in neurons in layer 6.
Immunohistochemistry-Paraffin: FoxP2 Antibody (CL5310) [NBP2-61412]

Immunohistochemistry-Paraffin: FoxP2 Antibody (CL5310) [NBP2-61412]

Immunohistochemistry-Paraffin: FoxP2 Antibody (CL5310) [NBP2-61412] - Staining of human cerebral cortex shows nuclear immunoreactivity in neurons in layer 6.
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Applications for FoxP2 Antibody (CL5310)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

2-10 ug/ml

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: PFA/Triton X-100

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FoxP2

FOXP2 encodes an evolutionarily conserved transcription factor expressed in fetal and adult brain. This transcription factor is a member of the forkhead/winged-helix (FOX) family of transcription factors, and contains a FOX DNA-binding domain and a large polyglutamine tract. Members of the FOX family of transcription factors are regulators of embryogenesis. The product of this gene is thought to be required for proper development of speech and language regions of the brain during embryogenesis. Although a point mutation in this gene has been associated with the KE pedigree segregating developmental verbal dyspraxia, no association between mutations in this gene and another speech disorder, autism, has been found. Four alternative transcripts encoding three different isoforms have been identified.

Long Name

Forkhead Box P2

Alternate Names

CAGH44, SPCH1, TNRC10

Gene Symbol

FOXP2

Additional FoxP2 Products

Product Documents for FoxP2 Antibody (CL5310)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for FoxP2 Antibody (CL5310)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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