FPR1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS2086

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NLS2086
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Chimpanzee (94%), Primate (94%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all FPR1 Antibodies »

Product Specifications

Immunogen

Synthetic 16 amino acid peptide from 2nd extracellular domain of human FPR1.

Epitope

2nd extracellular domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (94%), Orangutan (88%), Gibbon (81%).

Localization

Cell Membrane

Specificity

Human FPR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for FPR1 Antibody - BSA Free

Immunohistochemistry-Paraffin: FPR1 Antibody - BSA Free [NLS2086]

Immunohistochemistry-Paraffin: FPR1 Antibody - BSA Free [NLS2086]

Immunohistochemistry-Paraffin: FPR1 Antibody [NLS2086] - Analysis of anti-FPR1 antibody with human tonsil.

Applications for FPR1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

2 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: FPR1

Formyl peptide receptor 1, a Chemoattractant Receptor, mediates chemotaxis, degranulation, and superoxide production, as part of the inflammatory response. Bacterial N-formylmethionyl peptides and Annexin A1, specific ligands for FPR1, attract polymorphonuclear neutrophils to sites of infection. FPR receptors promote the phosphorylation and downregulation of CCR5, which has been shown to inhibit HIV infection. Therefore, ligands for an FPR receptor may be able to inhibit HIV infection. (WO0157074) FPR1 has been reported in blood monocytes, neutrophils, and phagocytes, as well as in liver, astrocytes, and microglia. ESTs have been isolated from B-cell/lung/testis, blood, brain, eye, heart, liver/spleen, kidney, lung, pancreas, placenta, spleen, and uterus libraries.

Long Name

Formyl Peptide Receptor 1

Alternate Names

fMLF-R, FMLP

Entrez Gene IDs

2357 (Human)

Gene Symbol

FPR1

Additional FPR1 Products

Product Documents for FPR1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for FPR1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.