Frizzled-5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49040

Novus Biologicals, part of Bio-Techne
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NBP2-49040
NBP2-49040-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (91%), Rat (91%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Frizzled-5 Antibodies »

Product Summary for Frizzled-5 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: WPERMSCDRLPVLGRDAEVLCMDYNRSEATTAPPRPFPAKPTLP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Frizzled-5 Antibody

Immunohistochemistry-Paraffin: Frizzled-5 Antibody [NBP2-49040]

Immunohistochemistry-Paraffin: Frizzled-5 Antibody [NBP2-49040]

Immunohistochemistry-Paraffin: Frizzled-5 Antibody [NBP2-49040] - Staining of human lateral ventricle shows moderate positivity in neurons.

Applications for Frizzled-5 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Frizzled-5

FZD5 is a Frizzled Receptor that mediates Wnt signaling. FZD5 is associated with limb bud and bone marrow stem cell development. FZD5 contributes to the activated state of fibroblast-like synoviocytes from patients with rheumatoid arthritis. Recently, FZD5 has been implicated in melanoma metastasis through the Wnt5a and PKC pathway. FZD5 has been reported to be expressed in fetal kidney, fetal and adult liver, fetal lung, and adult pancreas. ESTs have been isolated from bone, liver/spleen, placenta, and prostate libraries. FZD5 was cloned from a retina cDNA library.

Alternate Names

Frizzled5, Frz-5, FZ-5, FZD5

Gene Symbol

FZD5

Additional Frizzled-5 Products

Product Documents for Frizzled-5 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Frizzled-5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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