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Frizzled-6 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS4482

Novus Biologicals, part of Bio-Techne
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NLS4482

Key Product Details

Species Reactivity

Validated:

Human, Monkey, Primate

Predicted:

Bovine (94%), Canine (94%), Equine (94%), Mouse (94%), Orangutan (100%), Rabbit (94%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

Product Specifications

Immunogen

Synthetic 16 amino acid peptide from N-terminal extracellular domain of human Frizzled-6.

Epitope

N-Terminus extracellular domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Rat (88%), Opossum (88%), Turkey (88%), Chicken (88%), Bat (81%).

Specificity

Human Frizzled-6. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except FZD3 (50%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for Frizzled-6 Antibody - BSA Free

Immunohistochemistry-Paraffin: Frizzled-6 Antibody - BSA Free [NLS4482]

Immunohistochemistry-Paraffin: Frizzled-6 Antibody - BSA Free [NLS4482]

Immunohistochemistry-Paraffin: Frizzled-6 Antibody [NLS4482] - Human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: Frizzled-6 Antibody - BSA Free [NLS4482]

Immunohistochemistry-Paraffin: Frizzled-6 Antibody - BSA Free [NLS4482]

Immunohistochemistry-Paraffin: Frizzled-6 Antibody [NLS4482] - Analysis of anti-Frizzled-6 antibody with transfection control at 6 ug/ ml.
Immunohistochemistry-Paraffin: Frizzled-6 Antibody - BSA Free [NLS4482]

Immunohistochemistry-Paraffin: Frizzled-6 Antibody - BSA Free [NLS4482]

Immunohistochemistry-Paraffin: Frizzled-6 Antibody [NLS4482] - Analysis of anti-Frizzled-6 antibody with transfection control.

Applications for Frizzled-6 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry

3 - 6 ug/ml

Immunohistochemistry-Paraffin

10 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: Frizzled-6

FZD6 is a Frizzled Receptor for Wnt signaling proteins involved in patterning during development. Contrary to other Frizzled proteins, FZD6 does not contain a C-terminal PDZ domain-binding motif. FZD6 is widely expressed. The Drosophila homolog activates Dishevelled. FZD6 expression has been reported in brain, colon, heart, kidney, liver, lung, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine, testis, and thymus. Various tumor cell lines have also been shown to express FZD6. ESTs have been isolated from blood, brain, breast, connective tissue, liver, liver/spleen, lung, placenta, testis, thyroid, and vessel libraries. In addition, several ESTs have been isolated from tumor libraries.

Alternate Names

Frizzled6, FZD6

Entrez Gene IDs

8323 (Human)

Gene Symbol

FZD6

Additional Frizzled-6 Products

Product Documents for Frizzled-6 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Frizzled-6 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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