FRMPD2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77083

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all FRMPD2 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human FRMPD2. The immunogen is located within amino acids 80 - 130 of FRMPD2. Amino Acid Squence: SEDEQPDASQMHVYS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FRMPD2 Antibody - BSA Free

Western Blot: FRMPD2 AntibodyBSA Free [NBP1-77083]

Western Blot: FRMPD2 AntibodyBSA Free [NBP1-77083]

Western Blot: FRMPD2 Antibody [NBP1-77083] - Rat kidney tissue lysate with FRMPD2 antibody at (A) 1 and (B) 2 ug/mL.
Immunohistochemistry-Paraffin: FRMPD2 Antibody - BSA Free [NBP1-77083]

Immunohistochemistry-Paraffin: FRMPD2 Antibody - BSA Free [NBP1-77083]

Immunohistochemistry-Paraffin: FRMPD2 Antibody [NBP1-77083] - Mouse kidney tissue with FRMPD2 antibody at 5 ug/ml.

Applications for FRMPD2 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FRMPD2

The FERM and PDZ domain containing (FRMPD) protein family consists of four proteins that contain a FERM (Four-point-one, erzin, radixin, moesin) domain and at least one PDZ (PSD-95/Discs large/Zonula-occuldens-1) domain. FRMPD2 also contains an N-terminal KIND domain and three PDZ domains and is structurally similar to the protein tyrosine phosphatase PTP-BL. FRMPD2 is localized in a polarized fashion in epithelial cells at the basolateral membrane and partially co-localizes with the tight-junction marker protein Zonula-occuldens-1. Suppression of FRMPD2 expression via RNAi in Caco-2 cells results in an impairment of tight junction formation, indicating that FRMPD2 plays a major role in tight junction formation. Other experiments indicate that FRMPD2 is a binding partner to several catenin family members and recruitment of FRMPD2 to cell-cell contacts is dependent on E-cadherin-mediated cell-cell adhesion.

Alternate Names

FERM and PDZ domain containing 2

Gene Symbol

FRMPD2

UniProt

NP_001018081 (Human)

Additional FRMPD2 Products

Product Documents for FRMPD2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for FRMPD2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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