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FUS Antibody (BLR023E)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-76415

Recombinant Monoclonal Antibody.
Novus Biologicals, part of Bio-Techne
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NBP2-76415

Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Human, Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # BLR023E

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Immunogen sequence between amino acids 1 and 50

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FUS Antibody (BLR023E)

Western Blot: FUS Antibody (BLR023E) [NBP2-76415]

Western Blot: FUS Antibody (BLR023E) [NBP2-76415]

Western Blot: FUS Antibody (BLR023E) [NBP2-76415] - Detection of human and mouse FUS by WB of HeLa, HEK293T, Jurkat, TCMK-1, and NIH 3T3 lysate. Antibody: Rabbit anti-FUS recombinant monoclonal [BLR023E] (NBP2-76415). Secondary: HRP-conjugated goat anti-rabbit IgG.
Immunocytochemistry/ Immunofluorescence: FUS Antibody (BLR023E) [NBP2-76415]

Immunocytochemistry/ Immunofluorescence: FUS Antibody (BLR023E) [NBP2-76415]

Immunocytochemistry/Immunofluorescence: FUS Antibody (BLR023E) [NBP2-76415] - Detection of human FUS (red) in FFPE Hep-G2 cells by ICC-IF. Antibody: Rabbit anti-FUS recombinant monoclonal [BLR023E] (NBP2-76415). Secondary: DyLight 594-conjugated goat anti-rabbit IgG.
Immunohistochemistry: FUS Antibody (BLR023E) [NBP2-76415]

Immunohistochemistry: FUS Antibody (BLR023E) [NBP2-76415]

Immunohistochemistry: FUS Antibody (BLR023E) [NBP2-76415] - Section of human breast. Antibody: Rabbit anti-FUS recombinant monoclonal antibody [BLR023E] used at 1:250. Secondary: DyLight® 594- conjugated goat anti-rabbit IgG

Applications for FUS Antibody (BLR023E)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100 - 1:500

Immunohistochemistry

1:100 - 1:500

Immunohistochemistry-Paraffin

1:100 - 1:500

Immunoprecipitation

20 ul/mg lysate

Western Blot

1:1000
Application Notes
Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 2 - 8 C / 1 year from date of receipt

Background: FUS

FUS has been identified as a frequent translocation fusion partner of various transcription factors. FUS fusion genes have been shown to be associated with multiple tumor types which include liposarcoma, leukemia, histocytoma, and sarcoma. FUS is a multifunctional RNA-binding protein that associates with the nuclear matrix and Cajal bodies and appears to play a role in splicesome assembly, pre-mRNA splicing, DNA repair, transcriptional regulation and homologous recombination.

Alternate Names

75 kDa DNA-pairing protein, ALS6, amyotrophic lateral sclerosis 6, FUS1, fused in sarcoma, fusion (involved in t(12;16) in malignant liposarcoma), fusion gene in myxoid liposarcoma, fusion, derived from t(12;16) malignant liposarcoma, fus-like protein, heterogeneous nuclear ribonucleoprotein P2, HNRNPP2, Oncogene FUS, Oncogene TLS, POMp75, RNA-binding protein FUS, TLShnRNP-P2, Translocated in liposarcoma protein

Gene Symbol

FUS

Additional FUS Products

Product Documents for FUS Antibody (BLR023E)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for FUS Antibody (BLR023E)

This Product sold under License from Bethyl Laboratories, Inc.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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