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GABA-A R gamma 2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-49868

Novus Biologicals, part of Bio-Techne
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NBP1-49868

Key Product Details

Species Reactivity

Validated:

Mouse, Rat

Predicted:

Bovine (100%), Human (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Peptide with sequence C-NNATHLQERDE corresponding to internal region according to NP_000807.2, NP_944493.2.

Epitope

NNATHLQERDE - internal region

Specificity

This antibody is expected to recognize all reported isoforms: NP_944494.1; NP_000807.2; NP_944493.2. Note the aa numbers used in the name are from NP_944494.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for GABA-A R gamma 2 Antibody

Western Blot: GABA-A R gamma 2 Antibody [NBP1-49868]

Western Blot: GABA-A R gamma 2 Antibody [NBP1-49868]

Western Blot: GABA-A R gamma 2 Antibody [NBP1-49868] - Analysis of GABA -A Receptor gamma 2 in Mouse Brain lysate (35ug protein in RIPA buffer) using NBP1-49868 at 2 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for GABA-A R gamma 2 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:16000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 50 kDa band observed in mouse and rat brain lysates (calculated MW of 55.1 kDa band according to mouse NP_032099.1 and 54.1 kDa band according to rat NP_899156.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: GABA-A R gamma 2

GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics.

Long Name

gamma-Aminobutyric Acid Type A Receptor, gamma-2 Polypeptide

Alternate Names

GABAAR gamma 2, GABAARg2, GABRG2

Entrez Gene IDs

2566 (Human); 14406 (Mouse); 29709 (Rat)

Gene Symbol

GABRG2

Additional GABA-A R gamma 2 Products

Product Documents for GABA-A R gamma 2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GABA-A R gamma 2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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