GABA-AR alpha 6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-12973

Novus Biologicals, part of Bio-Techne
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NBP3-12973
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GABA-A R alpha 6 Antibodies »

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GABA-AR alpha 6. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

51 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Centrifuge briefly prior to opening.

Scientific Data Images for GABA-AR alpha 6 Antibody

Western Blot: GABA-AR alpha 6 Antibody [NBP3-12973]

Western Blot: GABA-AR alpha 6 Antibody [NBP3-12973]

Western Blot: GABA-AR alpha 6 Antibody [NBP3-12973] - Human tissue extract (30 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with GABA-AR alpha 6 antibody (NBP3-12973) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
Western Blot: GABA-AR alpha 6 Antibody [NBP3-12973]

Western Blot: GABA-AR alpha 6 Antibody [NBP3-12973]

Western Blot: GABA-AR alpha 6 Antibody [NBP3-12973] - Rat tissue extract (50 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with GABRA6 antibody (NBP3-12973) diluted at 1:1000.
Western Blot: GABA-AR alpha 6 Antibody [NBP3-12973]

Western Blot: GABA-AR alpha 6 Antibody [NBP3-12973]

Western Blot: GABA-AR alpha 6 Antibody [NBP3-12973] - Mouse tissue extract (50 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with GABRA6 antibody (NBP3-12973) diluted at 1:1000.
View 1 more images

Applications for GABA-AR alpha 6 Antibody

Application
Recommended Usage

Immunohistochemistry

Assay dependent

Immunohistochemistry-Paraffin

Assay dependent

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GABA-A R alpha 6

GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics. GABA (A) Receptors are comprised of subunits and these are further classified into 3 major groups (alpha, beta, and gamma). The subunits determine the pharmacological characteristics. The alpha 6 subunit is expressed in cerebellar granule cells. Though it is concentrated at synapses, it is found on extrasynaptic membranes, as well.

Long Name

gamma-Aminobutyric Acid Type A Receptor, alpha-6 Polypeptide

Alternate Names

GABAAR alpha 6, GABAARa6, GABRA6

Gene Symbol

GABRA6

Additional GABA-A R alpha 6 Products

Product Documents for GABA-AR alpha 6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GABA-AR alpha 6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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