GABARAP Antibody [DyLight 405]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-71771V

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Drosophila

Predicted:

Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all GABARAP Antibodies »

Product Specifications

Immunogen

A synthetic peptide made to a C-terminal region of the human GABARAP protein (within residues 50-117). [Swiss-Prot O95166]

Reactivity Notes

Predicted to react with rat based on 100% sequence homology. Drosophila reactivity reported in scientific literature (PMID: 28779125).

Localization

Endomembrane system. Cytoplasm. Golgi apparatus membrane. Note: Largely associated with intracellular membrane structures including the Golgi apparatus and post-synaptic cisternae. Colocalizes with microtubules.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for GABARAP Antibody [DyLight 405]

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: GABARAP

In several neurological diseases, GABARAP expression is related to autophagic functions. In Lewy body disease and Parkinson's disease, LC3 and GABARAP are often co-localized. Autophagy is regulated both at the transcriptional and post-transcriptional level, partially by the activation of GABARAP and other core autophagy machinery proteins. Although autophagy is usually considered to be important in cellular maintenance, and breakdown of proteins and organelles in cell death, it is becoming more and more clear that it plays an important role in the developmental process, including embryogenesis. This embryological effect seems to be partly regulated by GABARAP expression and activity.

Long Name

gamma-Aminobutyric Acid Type A Receptor Associated Protein

Alternate Names

Apg8p1, ATG8A, FLC3B, MM46

Gene Symbol

GABARAP

Additional GABARAP Products

Product Documents for GABARAP Antibody [DyLight 405]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GABARAP Antibody [DyLight 405]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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