GADD153/CHOP Antibody (RM485)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18837

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-18837
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # RM485

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all GADD153 Antibodies »

Product Specifications

Immunogen

A peptide corresponding to the N-terminus of human GADD153/CHOP (Uniprot # P35638)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GADD153/CHOP Antibody (RM485)

GADD153/CHOP Antibody (RM485)

Western Blot: GADD153/CHOP Antibody (RM485)[NBP3-18837]

Western Blot: GADD153/CHOP Antibody (RM485)[NBP3-18837]Western Blot of SW620 cell lysate using anti-DDIT3 rabbit monoclonal antibody (Clone RM485) at a 1:1000 dilution.

Applications for GADD153/CHOP Antibody (RM485)

Application
Recommended Usage

Immunohistochemistry

1:100 -1:200

Western Blot

1:1000 - 1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50% Glycerol/PBS, 1% BSA

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C.

Background: GADD153

GADD153 encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.

Long Name

Growth Arrest and DNA Damage-inducible Protein GADD153

Alternate Names

CEBP zeta, CHOP, CHOP10, DDIT3

Gene Symbol

DDIT3

Additional GADD153 Products

Product Documents for GADD153/CHOP Antibody (RM485)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GADD153/CHOP Antibody (RM485)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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