Galanin R1/GALR1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS4013

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human, Primate

Predicted:

Chimpanzee (95%), Orangutan (95%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all Galanin R1/GALR1 Antibodies »

Product Specifications

Immunogen

Synthetic 20 amino acid peptide from C-terminus of human Galanin R1/GALR1.

Epitope

C-terminal domain of human

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (95%), Monkey (89%).

Specificity

Human GALR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for Galanin R1/GALR1 Antibody - BSA Free

Immunohistochemistry-Paraffin: Galanin R1/GALR1 Antibody - BSA Free [NLS4013]

Immunohistochemistry-Paraffin: Galanin R1/GALR1 Antibody - BSA Free [NLS4013]

Immunohistochemistry-Paraffin: Galanin R1/GALR1 Antibody [NLS4013] - Analysis of anti-GALR1 antibody with human brain.

Applications for Galanin R1/GALR1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

7 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: Galanin R1/GALR1

GalR1 is a Galanin Receptor that mediates the effects of the peptide galanin in a wide variety of tissues. Unlike GalR2, the primary signaling mechanism of GalR1 is by inhibiting adenylate cyclase through Gi. GalR1 regulates the GnRH neuroendocrine axis with its expression in POMC neurons. Pathogens like E. coli can cause diarrhea by increasing expression of Galanin Receptor 1 in the epithelial cells lining the colon, resulting in increased secretion of colonocyte chloride and fluid. GalR1 has been reported in brain, spinal cord, small intestine, colon, and eye. ESTs have been isolated from nerve and fetal lung/testis/B-cell libraries.

Long Name

Galanin Receptor Type 1

Alternate Names

GAL1, GalaninR1, GALNR1, GALR1

Entrez Gene IDs

2587 (Human)

Gene Symbol

GALR1

Additional Galanin R1/GALR1 Products

Product Documents for Galanin R1/GALR1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Galanin R1/GALR1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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