GAP-43 Antibody (S01-4F6)
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-20078
Recombinant Monoclonal Antibody
Key Product Details
Species Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot
Label
Unconjugated
Antibody Source
Recombinant Monoclonal Rabbit IgG Clone # S01-4F6
Concentration
0.3 mg/ml
Product Specifications
Immunogen
A synthetic peptide of human GAP-43 (Uniprot # P17677)
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG
Theoretical MW
46 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Scientific Data Images for GAP-43 Antibody (S01-4F6)
![Western Blot: GAP-43 Antibody (S01-4F6) [NBP3-20078]](https://resources.bio-techne.com/images/products/GAP-43-Antibody-S01-4F6-Western-Blot-NBP3-20078-img0002.jpg "Western Blot: GAP-43 Antibody (S01-4F6) [NBP3-20078]")
Western Blot: GAP-43 Antibody (S01-4F6) [NBP3-20078]
Western Blot: GAP-43 Antibody (S01-4F6) [NBP3-20078] - Western blot detection of GAP-43 in Rat Brain lysates using NBP3-20078 (1:1000 diluted). Predicted band size: 25kDa. Observed band size: 46kDa.![Immunohistochemistry-Paraffin: GAP-43 Antibody (S01-4F6) [NBP3-20078]](https://resources.bio-techne.com/images/products/GAP-43-Antibody-S01-4F6-Immunohistochemistry-Paraffin-NBP3-20078-img0001.jpg "Immunohistochemistry-Paraffin: GAP-43 Antibody (S01-4F6) [NBP3-20078]")
Immunohistochemistry-Paraffin: GAP-43 Antibody (S01-4F6) [NBP3-20078]
Immunohistochemistry-Paraffin: GAP-43 Antibody (S01-4F6) [NBP3-20078] - Immunohistochemistry of GAP-43 in paraffin-embedded Human Brain using NBP3-20078 at dilution 1/50Applications for GAP-43 Antibody (S01-4F6)
Application
Recommended Usage
Immunohistochemistry
1/50
Western Blot
1/1000
Formulation, Preparation, and Storage
Purification
Affinity purified
Formulation
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
Preservative
0.01% Sodium Azide
Concentration
0.3 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: GAP-43
Heterozygous GAP3 knockout mice with GAP-43 levels reduced by one-half display significant memory impairments in cued conditioning, or on tests of nociceptive or auditory perception. Differentiating neurons that do not express GAP-43 show mislocalization of the centrosome and mitotic spindles, particularly in neurogenic cell divisions. Therefore, the neuronal precursor pool in the cerebellum fails to grow resulting in a cerebellum that is significantly smaller than normal. Total GAP-43 deletion is lethal within days of birth, demonstrating that GAP-43 is critical for the proper development of the mammalian CNS.
Long Name
Growth Associated Protein 43
Alternate Names
B-50, Basp2, GAP43, Neuromodulin
Gene Symbol
GAP43
Additional GAP-43 Products
Product Documents for GAP-43 Antibody (S01-4F6)
Product Specific Notices for GAP-43 Antibody (S01-4F6)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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