GAP-43 [p Ser41] Antibody - Azide and BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-05419
Key Product Details
Species Reactivity
Human, Mouse, Rat
Applications
Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Format
Azide and BSA Free
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
A synthetic phosphorylated peptide around S41 of human GAP-43 (NP_002036.1). QASFR
Modification
p Ser41
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Scientific Data Images for GAP-43 [p Ser41] Antibody - Azide and BSA Free
![Immunocytochemistry/ Immunofluorescence: GAP-43 [p Ser41] Antibody - Azide and BSA Free [NBP3-05419]](https://resources.bio-techne.com/images/products/GAP-43-[p-Ser41]-Antibody-Immunocytochemistry-Immunofluorescence-NBP3-05419-img0001.jpg "Immunocytochemistry/ Immunofluorescence: GAP-43 [p Ser41] Antibody - Azide and BSA Free [NBP3-05419]")
Immunocytochemistry/ Immunofluorescence: GAP-43 [p Ser41] Antibody - Azide and BSA Free [NBP3-05419]
Immunocytochemistry/Immunofluorescence: GAP-43 [p Ser41] Antibody [NBP3-05419] - Immunofluorescence analysis of methanol-fixed HeLa cells using GAP-43 antibody (NBP3-05419).Applications for GAP-43 [p Ser41] Antibody - Azide and BSA Free
Application
Recommended Usage
Western Blot
1:500 - 1:2000
Formulation, Preparation, and Storage
Purification
Affinity purified
Formulation
PBS with 50% glycerol, pH7.3.
Format
Azide and BSA Free
Preservative
0.01% Thimerosal
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at -20C. Avoid freeze-thaw cycles.
Background: GAP-43
Heterozygous GAP3 knockout mice with GAP-43 levels reduced by one-half display significant memory impairments in cued conditioning, or on tests of nociceptive or auditory perception. Differentiating neurons that do not express GAP-43 show mislocalization of the centrosome and mitotic spindles, particularly in neurogenic cell divisions. Therefore, the neuronal precursor pool in the cerebellum fails to grow resulting in a cerebellum that is significantly smaller than normal. Total GAP-43 deletion is lethal within days of birth, demonstrating that GAP-43 is critical for the proper development of the mammalian CNS.
Long Name
Growth Associated Protein 43
Alternate Names
B-50, Basp2, GAP43, Neuromodulin
Gene Symbol
GAP43
Additional GAP-43 Products
Product Documents for GAP-43 [p Ser41] Antibody - Azide and BSA Free
Product Specific Notices for GAP-43 [p Ser41] Antibody - Azide and BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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⚠ WARNING: This product can expose you to chemicals including Methotrexate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov