GCAP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-55158

Novus Biologicals, part of Bio-Techne
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NBP2-55158
NBP2-55158-25ul
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Key Product Details

Species Reactivity

Validated:

Human, Monkey

Cited:

Primate - Macaca mulatta (Rhesus Macaque)

Predicted:

Rat (90%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin

Cited:

Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GCAP1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: EYVAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIQAIRAINPCSDTTMTAEEFTDTVFSKIDVNGDGELSLEEFIEGVQKDQMLLDTLTRSLDLTRIVRRLQNGEQDEEGADEAAEAAG

Reactivity Notes

Use in Monkey reported in scientific literature (PMID:35024589). Mouse( 88%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GCAP1 Antibody

Immunohistochemistry-Paraffin: GCAP1 Antibody [NBP2-55158]

Immunohistochemistry-Paraffin: GCAP1 Antibody [NBP2-55158]

Immunohistochemistry-Paraffin: GCAP1 Antibody [NBP2-55158] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry-Paraffin: GCAP1 Antibody [NBP2-55158]

Immunohistochemistry-Paraffin: GCAP1 Antibody [NBP2-55158]

Immunohistochemistry-Paraffin: GCAP1 Antibody [NBP2-55158] - Staining of human duodenum shows no positivity in glandular cells as expected.
GCAP1 Antibody

Immunohistochemistry-Paraffin: GCAP1 Antibody [NBP2-55158] -

Immunohistochemistry-Paraffin: GCAP1 Antibody [NBP2-55158] -Staining of human retina shows moderate to strong positivity in photoreceptor layer as well as outer plexiform layer.
View 1 more images

Applications for GCAP1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:5000 - 1:10000

Immunohistochemistry-Frozen

Reported in scientific literature (PMID:35024589)

Immunohistochemistry-Paraffin

1:5000 - 1:10000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended..

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GCAP1

The GCAP1 gene plays a role in the recovery of retinal photoreceptors from photobleaching. In the recovery phase, thephototransduction messeneger cGMP is replenished by retinal guanylyl cyclase-1 (GC1). GC1 is activated by decreasingCa(2+) concentrations follo

Alternate Names

C6orf131, chromosome 6 open reading frame 131, CORD14, GCAP 1, GCAP1photoreceptor 1, GCAPGUCA, Guanylate cyclase activator 1A, guanylate cyclase activator 1A (retina), guanylin 1, retina, guanylyl cyclase-activating protein 1, GUCA1

Gene Symbol

GUCA1A

Additional GCAP1 Products

Product Documents for GCAP1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GCAP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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