GCKR Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-28910

Novus Biologicals, part of Bio-Techne
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NBP1-28910
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Key Product Details

Species Reactivity

Validated:

Mouse, Rat

Predicted:

Human (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all GCKR Antibodies »

Product Specifications

Immunogen

Peptide with sequence KRFQHVIETPEPGK -C corresponding to N-Terminus according to NP_001477.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Theoretical MW

69 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for GCKR Antibody

Western Blot: GCKR Antibody [NBP1-28910]

Western Blot: GCKR Antibody [NBP1-28910]

Western Blot: GCKR Antibody [NBP1-28910] - (0.1ug/ml) staining of Rat Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for GCKR Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:8000

Western Blot

0.1 - 0.3 ug/ml
Application Notes
WB: Approx. 70 kDa band observed in mouse and rat liver lysates (calculated MW of 68.7 kDa band according to human NP_001477.1 and of 68.9 kDa band according to rat NP_037252.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: GCKR

This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq]

Alternate Names

FGQTL5, GKRP, glucokinase (hexokinase 4) regulator, glucokinase (hexokinase 4) regulatory protein, Glucokinase regulator, glucokinase regulatory protein

Entrez Gene IDs

2646 (Human); 231103 (Mouse); 25658 (Rat)

Gene Symbol

GCKR

UniProt

Q14397 (Human)

Additional GCKR Products

Product Documents for GCKR Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GCKR Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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