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GDF-11/BMP-11 Antibody (3G6)

Novus Biologicals, part of Bio-Techne | Catalog # H00010220-M01

Novus Biologicals, part of Bio-Techne
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H00010220-M01

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 3G6

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

GDF11 (NP_005802, 310 a.a. ~ 407 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. ESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGQCEYMFMQKYPHTHLVQQANPRGSAGPCCTPTKMSPINMLYFNDKQQIIYGKIPGMVVDRCGCS

Reactivity Notes

Other species not tested.

Specificity

GDF11 - growth differentiation factor 11

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Scientific Data Images for GDF-11/BMP-11 Antibody (3G6)

Immunohistochemistry-Paraffin: GDF-11/BMP-11 Antibody (3G6) [H00010220-M01]

Immunohistochemistry-Paraffin: GDF-11/BMP-11 Antibody (3G6) [H00010220-M01]

Immunohistochemistry-Paraffin: GDF-11/BMP-11 Antibody (3G6) [H00010220-M01] - Analysis of monoclonal antibody to GDF11 on formalin-fixed paraffin-embedded human pancreas. Antibody concentration 3 ug/ml.

Applications for GDF-11/BMP-11 Antibody (3G6)

Application
Recommended Usage

ELISA

1:100-1:2000

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500
Application Notes
Antibody reactive against recombinant protein on ELISA. It has also been used for immunohistochemistry on paraffin sections. Antigen retrieval using 1X citrate buffer (pH 6.0) in pressure cooker under 125? for 4min and under 90? for 45min is recommended.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: GDF-11/BMP-11

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.

Long Name

Growth Differentiation Factor 11

Alternate Names

BMP-11, BMP11, GDF11

Entrez Gene IDs

10220 (Human)

Gene Symbol

GDF11

OMIM

603936 (Human)

Additional GDF-11/BMP-11 Products

Product Documents for GDF-11/BMP-11 Antibody (3G6)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GDF-11/BMP-11 Antibody (3G6)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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