GDF-5/BMP-14 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16631

Novus Biologicals, part of Bio-Techne
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NBP2-16631
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Bovine (97%), Mouse (95%), Porcine (98%), Rabbit (92%). Backed by our 100% Guarantee.

Applications

Functional Assay, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GDF-5/BMP-14 Antibodies »

Product Summary for GDF-5/BMP-14 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human GDF-5/BMP-14. The exact sequence is proprietary.

Reactivity Notes

Chicken (83%).

Localization

Secreted

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for GDF-5/BMP-14 Antibody

Western Blot: GDF-5/BMP-14 Antibody [NBP2-16631]

Western Blot: GDF-5/BMP-14 Antibody [NBP2-16631]

Western Blot: GDF5 Antibody [NBP2-16631] - Sample (30 ug of whole cell lysate) A: IMR32 7. 5% SDS PAGE gel, diluted at 1:1000.
Immunohistochemistry-Paraffin: GDF-5/BMP-14 Antibody [NBP2-16631]

Immunohistochemistry-Paraffin: GDF-5/BMP-14 Antibody [NBP2-16631]

Immunohistochemistry-Paraffin: GDF5 Antibody [NBP2-16631] - Immunohistochemical analysis of paraffin-embedded Colon CA, using antibody at 1:250 dilution.
GDF-5/BMP-14 Antibody

Western Blot: GDF-5/BMP-14 Antibody [NBP2-16631] -

Western Blot: GDF-5/BMP-14 Antibody [NBP2-16631] - Various whole cell extracts (30 Âug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with GDF5 antibody diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.

Applications for GDF-5/BMP-14 Antibody

Application
Recommended Usage

Functional Assay

Assay dependent

Immunocytochemistry/ Immunofluorescence

Assay dependent

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: GDF-5/BMP-14

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type; brachydactyly, type C; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development. [provided by RefSeq]

Long Name

Growth Differentiation Factor 5

Alternate Names

BMP-14, CDMP-1, GDF5

Gene Symbol

GDF5

UniProt

P43026

Additional GDF-5/BMP-14 Products

Product Documents for GDF-5/BMP-14 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for GDF-5/BMP-14 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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