GFR alpha-3/GDNF R alpha-3 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77035

Novus Biologicals, part of Bio-Techne
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NBP1-77035
NBP1-77035-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all GFR alpha-3/GDNF R alpha-3 Antibodies »

Product Summary for GFR alpha-3/GDNF R alpha-3 Antibody - BSA Free

Immunogen

Antibody was raised against a 14 amino acid peptide near the center of murine GFR alpha 3. The immunogen is located within the last 50 amino acids of GFR alpha 3. Amino Acid Squence: RFHSQLFSQDWPHPT

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

43 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for GFR alpha-3/GDNF R alpha-3 Antibody - BSA Free

Western Blot: GFR alpha-3/GDNF R alpha-3 AntibodyBSA Free [NBP1-77035]

Western Blot: GFR alpha-3/GDNF R alpha-3 AntibodyBSA Free [NBP1-77035]

Western Blot: GFR alpha-3/GDNF R alpha-3 Antibody [NBP1-77035] - Crude cell membrane fractions of mouse heart (H), spleen (S), kidney (K), liver (L), and brain (B), respectively, with GFR alpha 3 antibody at 1:500 dilution.
Immunocytochemistry/ Immunofluorescence: GFR alpha-3/GDNF R alpha-3 Antibody - BSA Free [NBP1-77035]

Immunocytochemistry/ Immunofluorescence: GFR alpha-3/GDNF R alpha-3 Antibody - BSA Free [NBP1-77035]

Immunocytochemistry/Immunofluorescence: GFR alpha-3/GDNF R alpha-3 Antibody [NBP1-77035] - Staining of GFR alpha 3 in mouse kidney tissue with GFR alpha 3 antibody at 5 ug/ml.
Immunohistochemistry-Paraffin: GFR alpha-3/GDNF R alpha-3 Antibody - BSA Free [NBP1-77035]

Immunohistochemistry-Paraffin: GFR alpha-3/GDNF R alpha-3 Antibody - BSA Free [NBP1-77035]

Immunohistochemistry-Paraffin: GFR alpha-3/GDNF R alpha-3 Antibody [NBP1-77035] - Staining of GFR alpha 3 in mouse kidney tissue with GFR alpha 3 antibody at 5 ug/ml.
View 1 more images

Applications for GFR alpha-3/GDNF R alpha-3 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

5 ug/ml

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

0.5 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Ion exchange chromatography

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GFR alpha-3/GDNF R alpha-3

Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN) play essential roles in the control of vertebrate neuron survival and differentiation. A new member of the GDNF family was recently identified and designated persephin. Physiological responses to these neurotrophic factors require two receptor subunits, the novel glycosylphosphadidylinositol linked protein GFRalpha and Ret receptor tyrosine kinase GFRbeta. Following the findings of GFRalpha-1 and -2, a novel receptor in GFRalpha family was identified very recently from human and mouse and designated GFRalpha-3. GFRalpha-3 binds persephin, thus, persephin, GFRalpha-3, and Ret PTK form a complex to transduce persephin signal and to mediate persephin function.

Long Name

Glial Cell line-derived Neurotrophic Factor Receptor alpha 3

Alternate Names

GDNF R alpha-3, GFR alpha3, GFRa-3, GFRA3

Entrez Gene IDs

2676 (Human); 14587 (Mouse)

Gene Symbol

GFRA3

UniProt

O35118 (Mouse)

Additional GFR alpha-3/GDNF R alpha-3 Products

Product Documents for GFR alpha-3/GDNF R alpha-3 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for GFR alpha-3/GDNF R alpha-3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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