GGCX Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-51964

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP1-51964
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Canine (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all GGCX Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-PPESNPDPVHSE corresponding to C-Terminus according to NP_000812.2, NP_001135741.1.

Epitope

C-PPESNPDPVHSE

Specificity

This antibody is expected to recognize both isoforms (NP_000812.2; NP_001135741.1).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for GGCX Antibody

Western Blot: GGCX Antibody [NBP1-51964]

Western Blot: GGCX Antibody [NBP1-51964]

Western Blot: GGCX Antibody [NBP1-51964] - Analysis of GGCX in Human Muscle lysate (35ug protein in RIPA buffer) using NBP1-51964 at 0.3 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.
Immunohistochemistry-Paraffin: GGCX Antibody [NBP1-51964]

Immunohistochemistry-Paraffin: GGCX Antibody [NBP1-51964]

Immunohistochemistry-Paraffin: GGCX Antibody [NBP1-51964] - Staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Applications for GGCX Antibody

Application
Recommended Usage

Immunohistochemistry

5 - 10 ug/ml

Immunohistochemistry-Paraffin

5 - 10 ug/ml

Peptide ELISA

Detection limit 1:32000

Western Blot

0.3 - 1 ug/ml
Application Notes
WB: Approx. 85 kDa band observed in human muscle lysates (calculated MW of 85 kDa band according to NP_000812.2). IHC-P: Human kidney shows distinct staining in the cytoplasm of epthelial cells.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: GGCX

Gamma-glutamyl carboxylase (GGCX) mediates the vitamin K-dependent carboxylation of glutamate residues to calcium binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. GGCX accomplishes the posttranslational modification required for the activity of all of the vitamin K-dependent proteins. These include some of the blood coagulation and anticoagulation proteins as well as bone gamma-carboxyglutamic acid (Gla) protein (BGLAP) and bone matrix protein (MGP)

Long Name

Gamma-Glutamyl Carboxylase

Alternate Names

VKCFD1

Entrez Gene IDs

2677 (Human)

Gene Symbol

GGCX

UniProt

NP_000812.2 (Human)

Additional GGCX Products

Product Documents for GGCX Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for GGCX Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.