GGCX Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-59394

Novus Biologicals, part of Bio-Techne
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NBP1-59394
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all GGCX Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to GGCX(gamma-glutamyl carboxylase) The peptide sequence was selected from the middle region of GGCX. Peptide sequence FLLRKLYVFRRSFLMTCISLRNLILGRPSLEQLAQEVTYANLRPFEAVGE. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for GGCX Antibody

Western Blot: GGCX Antibody [NBP1-59394]

Western Blot: GGCX Antibody [NBP1-59394]

Western Blot: GGCX Antibody [NBP1-59394] - Jurkat, Antibody Dilution: 1.0 ug/ml GGCX is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells.

Immunohistochemistry-Paraffin: GGCX Antibody [NBP1-59394] -

Immunohistochemistry-Paraffin: GGCX Antibody [NBP1-59394] - Formalin Fixed Paraffin; Embedded Tissue: Human Adult Liver; Observed Staining: Cytoplasm in hepatocytes, strong signal, wide tissue distribution; Primary Antibody Concentration: 1:100
Western Blot: GGCX Antibody [NBP1-59394]

Western Blot: GGCX Antibody [NBP1-59394]

Western Blot: GGCX Antibody [NBP1-59394] - MCF-7 whole cell lysates, concentration 0.2-1 ug/ml.

Applications for GGCX Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GGCX

GGCX is an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency.Gamma-glutamyl carboxylase accomplishes the posttranslational modification required for the activity of all of the vitamin K-dependent proteins (Wu et al., 1991 [PubMed 1749935]). These include some of the blood coagulation and anticoagulation proteins as well as bone gamma-carboxyglutamic acid (Gla) protein (BGLAP; MIM 112260) and bone matrix protein (MGP; MIM 154870).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Long Name

Gamma-Glutamyl Carboxylase

Alternate Names

VKCFD1

Gene Symbol

GGCX

UniProt

P38435 (Human)

Additional GGCX Products

Product Documents for GGCX Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GGCX Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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