Girdin Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76253

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Girdin Antibodies »

Product Summary for Girdin Antibody - BSA Free

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus human Girdin. The immunogen is located within the last 50 amino acids of Girdin. Amino Acid Squence: DKVQESRNSKSRSREQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Girdin Antibody - BSA Free

Western Blot: Girdin AntibodyBSA Free [NBP1-76253]

Western Blot: Girdin AntibodyBSA Free [NBP1-76253]

Western Blot: Girdin Antibody [NBP1-76253] - Rat brain tissue lysate with Girdin antibody at (A) 1 and (B) 2 ug/mL.

Immunohistochemistry: Girdin Antibody [NBP1-76253] -

Immunohistochemistry: Girdin Antibody [NBP1-76253] - Human brain tissue at 20 ug/ml

Applications for Girdin Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Western Blot

1-2 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Girdin

Girdin is a Galpha-interacting protein that can enhance the activation of the protein kinase Akt, remodel the actin cytoskeleton, and is thought to be involved in the regulation of cell migration and cancer metastasis. It has recently been shown that Girdin interacts with Disrupted-in-Schizophrenia 1 (DISC1), a susceptibility gene for major psychiatric disorders. DISC1 is thought to be involved in the migration, positioning and differentiation of dentate granule cells (DGCs) during development; depletion of Girdin or blocking the Girdin-DISC1 interaction results in defects in axonal sprouting in the CA3 region of the hippocampus and overextended migration of mispositioning of DGCs, suggesting the Girdin plays a role in postnatal neurogenesis in the dentate gyrus.

Long Name

Girders of Actin Filament

Alternate Names

APE, CCDC88A, GIV, GRDN, HkRP1

Gene Symbol

CCDC88A

UniProt

NP_060554 (Human)

Additional Girdin Products

Product Documents for Girdin Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Girdin Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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