Gli2 belongs to the C2H2 type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors that bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. Gli2 is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes Greig cephalopolysyndactyly syndrome, Pallister Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.

Long Name

GLI-Kruppel family member GLI2

Alternate Names

GLI2, THP2

Gene Symbol

GLI2

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Product Documents for GLI-2 Antibody (524409) [HRP]

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Product Specific Notices for GLI-2 Antibody (524409) [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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GLI-2 Antibody (524409) [HRP]

Novus Biologicals, part of Bio-Techne | Catalog # MAB35262H

Key Product Details

Species Reactivity

Validated:

Applications

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Product Summary for GLI-2 Antibody (524409) [HRP]

Immunogen

Clonality

Host

Isotype

Applications for GLI-2 Antibody (524409) [HRP]

Immunohistochemistry

Immunohistochemistry-Paraffin

Formulation, Preparation, and Storage

Purification

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Preservative

Concentration

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Stability & Storage

Background: GLI-2