Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Flow Cytometry, Immunocytochemistry

Label

DyLight 550 (Excitation = 562 nm, Emission = 576 nm)

Antibody Source

Recombinant Monoclonal Mouse IgG2A Clone # 413801

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all GLP-2R Antibodies »

Product Specifications

Immunogen

HEK293 human embryonic kidney cell line transfected with human GLP-2R
Met1-Ile553
Accession # O95838

Specificity

Detects human GLP‑2R. Stains human GLP-2R transfectants but not irrelevant transfectants.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for GLP-2R Antibody (413801) [DyLight 550]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: GLP-2R

GLP2R, a Glucagon Receptor, is closely related to the Glucagon Receptor and to the GLP1 Receptor. The glucagon-like peptides (GLP-1 and GLP-2) are proglucagon-derived peptides cosecreted from gut endocrine cells in response to nutrient ingestion. The actions of GLP-2 are mediated by the GLP-2 receptor expressed on subsets of enteric nerves and enteroendocrine cells in the stomach and small and large intestine. Activation of GLP2R signaling promotes expansion of the mucosal epithelium indirectly via activation of growth and anti-apoptotic pathways. GLP2R, through its ligand glucagon-like peptide 2 (GLP2), has been shown to prevent intestinal hypoplasia resulting from total parenteral nutrition. GLP2R has been reported primarily in the gastrointestinal tract, including intestine and stomach. In rats, GLPR2 has been shown in brain and lung. An EST has been isolated from a lung cancer library.

Long Name

Glucagon-like Peptide 2 Receptor

Alternate Names

GLP2R

Gene Symbol

GLP2R

Additional GLP-2R Products

Product Documents for GLP-2R Antibody (413801) [DyLight 550]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for GLP-2R Antibody (413801) [DyLight 550]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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