GLP/EHMT1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57166

Novus Biologicals, part of Bio-Techne
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NBP2-57166
NBP2-57166-25ul
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Key Product Details

Species Reactivity

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence

Cited:

IF/IHC, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GLP/EHMT1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: ADGETNGSCENSDASSHANAAKHTQDSARVNPQDGTNTLTRIAENGVSERDSEAAKQNHVTADDFVQTSVIGSNGYILNKPALQAQPLRTTSTLASSLPGHAAKTLPGGAGKGRTPSAFPQTPAAPPATL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GLP/EHMT1 Antibody

Immunocytochemistry/ Immunofluorescence: GLP/EHMT1 Antibody [NBP2-57166]

Immunocytochemistry/ Immunofluorescence: GLP/EHMT1 Antibody [NBP2-57166]

Immunocytochemistry/Immunofluorescence: GLP/EHMT1 Antibody [NBP2-57166] - Staining of human cell line MCF7 shows localization to nucleoplasm & nuclear bodies. Antibody staining is shown in green.

Applications for GLP/EHMT1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100. Please note that WB was reported in PMID:35176430, 35139903,which used a previous lot that is no longer available. The current lot of this antibody is not validated for use in WB. Please contact technical services if you have any questions.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GLP/EHMT1

Euchromatic histone-lysine N-methyltransferase 1 (EHMT1) is a histone methyltransferase that catalyzes the methylation of lysine-9 of histone H3 (H3-K9). H3-K9 histone methylation is restricted to euchromatin and functions to epigenetically silence gene transcription. Loss of function mutations in EHMT1 cause the 9q34 subtelomeric deletion syndrome, a syndrome characterized by severe mental retardation, hypotonia, brachy(micro)cephaly, heart defects, and distinct facial anomalies. Alternate names for EHMT1 include histone H3-K9 methyltransferase 5, H3-K9-HMTase5, eu-HMTase, G9a-like protein 1, GLP1, lysine N-methyltransferase 1D, EUHMTASE1, KMT1D, and KIAA1876.

Long Name

G9a-like Protein 1/Euchromatic Histone-Lysine N-Methyltransferase 1

Alternate Names

DEL9q34, EHMT1, Eu-HMTase1, KMT1D, Lysine N-methyltransferase 1D

Gene Symbol

EHMT1

Additional GLP/EHMT1 Products

Product Documents for GLP/EHMT1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GLP/EHMT1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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