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GLRB Antibody (3B8A8) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-61774

Novus Biologicals, part of Bio-Techne
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NBP2-61774
NBP2-61774-0.025ml

Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 3B8A8

Format

BSA Free

Concentration

1 mg/ml

Product Summary for GLRB Antibody (3B8A8) - BSA Free

Immunogen

Purified recombinant fragment of human GLRB (AA: extra 23-160) expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Theoretical MW

56.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for GLRB Antibody (3B8A8) - BSA Free

Western Blot: GLRB Antibody (3B8A8)BSA Free [NBP2-61774]

Western Blot: GLRB Antibody (3B8A8)BSA Free [NBP2-61774]

Western Blot: GLRB Antibody (3B8A8) [NBP2-61774] - Analysis using GLRB mAb against human GLRB (AA: extra 23-160) recombinant protein. (Expected MW is 41.8 kDa)
Immunocytochemistry/ Immunofluorescence: GLRB Antibody (3B8A8) - BSA Free [NBP2-61774]

Immunocytochemistry/ Immunofluorescence: GLRB Antibody (3B8A8) - BSA Free [NBP2-61774]

Immunocytochemistry/Immunofluorescence: GLRB Antibody (3B8A8) [NBP2-61774] - Analysis of Hela cells using GLRB mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Goat anti-Mouse IgG (H+L) DyLight 488 secondary antibody was used.
Western Blot: GLRB Antibody (3B8A8)BSA Free [NBP2-61774]

Western Blot: GLRB Antibody (3B8A8)BSA Free [NBP2-61774]

Western Blot: GLRB Antibody (3B8A8) [NBP2-61774] - Analysis using GLRB mAb against HEK293 (1) and GLRB (AA: extra 23-160)-hIgGFc transfected HEK293 (2) cell lysate.

Applications for GLRB Antibody (3B8A8) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Flow Cytometry

1:200-1:400

Immunocytochemistry/ Immunofluorescence

1:200-1:1000

Western Blot

1:200-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GLRB

This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.

Alternate Names

beta subunit, Glycine receptor 58 kDa subunit, glycine receptor, beta

Gene Symbol

GLRB

Additional GLRB Products

Product Documents for GLRB Antibody (3B8A8) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GLRB Antibody (3B8A8) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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