Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86084

Novus Biologicals, part of Bio-Techne
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NBP1-86084
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%), Rat (93%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DVLVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTMSALWNLQYCEFDDQEVFVEVYNLTADPDQITNIAKTIDPELLGKMNYRLMMLQSCSGPTCRTPGVFDPGYRFDPRLMFSNRGSVRTRRF

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody

Western Blot: Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody [NBP1-86084]

Western Blot: Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody [NBP1-86084]

Western Blot: Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody [NBP1-86084] - Analysis in control (vector only transfected HEK293T lysate) and GNS over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody [NBP1-86084]

Immunohistochemistry-Paraffin: Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody [NBP1-86084]

Immunohistochemistry-Paraffin: Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody [NBP1-86084] - Staining of human adrenal gland shows strong cytoplasmic positivity in granular pattern.

Applications for Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Glucosamine (N-acetyl)-6-Sulfatase/GNS

The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome. [provided by RefSeq]

Alternate Names

Glucosamine6Sulfatase, GNS

Gene Symbol

GNS

Additional Glucosamine (N-acetyl)-6-Sulfatase/GNS Products

Product Documents for Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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