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Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38583

Novus Biologicals, part of Bio-Techne
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NBP2-38583
NBP2-38583-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: NYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNFEPFFMMIATPAPHSPWTAAPQYQKAFQNVFAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody

Immunohistochemistry-Paraffin: Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody [NBP2-38583]

Immunohistochemistry-Paraffin: Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody [NBP2-38583]

Immunohistochemistry-Paraffin: Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody [NBP2-38583] - Staining of human skeletal muscle shows low expression as expected.
Immunohistochemistry: Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody [NBP2-38583]

Immunohistochemistry: Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody [NBP2-38583]

Immunohistochemistry: Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody [NBP2-38583] - Staining of human kidney shows strong cytoplasmic positivity in renal tubules.
Immunohistochemistry-Paraffin: Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody [NBP2-38583]

Immunohistochemistry-Paraffin: Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody [NBP2-38583]

Immunohistochemistry-Paraffin: Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody [NBP2-38583] - Staining of human adrenal gland shows high expression.

Applications for Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Glucosamine (N-acetyl)-6-Sulfatase/GNS

The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome. [provided by RefSeq]

Alternate Names

Glucosamine6Sulfatase, GNS

Gene Symbol

GNS

UniProt

Additional Glucosamine (N-acetyl)-6-Sulfatase/GNS Products

Product Documents for Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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