Glucosylceramidase/GBA Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00002629-B01P

Novus Biologicals, part of Bio-Techne
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H00002629-B01P
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Glucosylceramidase/GBA Antibodies »

Product Specifications

Immunogen

GBA (AAH03356.1, 1 a.a. - 536 a.a.) full-length human protein. MEFSSPSREECPKPLSRVSIMAGSLTGLLLLQAVSWASGARPCIPKSFGYSSVVCVCNATYCDSFDPPTFPALGTFSRYESTRSGRRMELSMGPIQANHTGTGLLLTLQPEQKFQKVKGFGGAMTDAAALNILALSPPAQNLLLKSYFSEEGIGYNIIRVPMASCDFSIRTYTYADTPDDFQLHNFSLPEEDTKLKIPLIHRALQLAQRPVSLLASPWTSPTWLKTNGAVNGKGSLKGQPGDIYHQTWARYFVKFLDAYAEHKLQFWAVTAENEPSAGLLSGYPFQCLGFTPEHQRDFIARDLGPTLANSTHHNVRLLMLDDQRLLLPHWAKVVLTDPEAAKYVHGIAVHWYLDFLAPAKATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVVGWTDWNLALNPEGGPNWVRNFVDSPIIVDITKDTFYKQPMFYHLGHFSKFIPEGSQRVGLVASQKNDLDAVALMHPDGSAVVVVLNRSSKDVPLTIKDPAVGFLETISPGYSIHTYLWRRQ

Specificity

GBA - glucosidase, beta; acid (includes glucosylceramidase),

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for Glucosylceramidase/GBA Antibody

Western Blot: Glucosylceramidase/GBA Antibody [H00002629-B01P]

Western Blot: Glucosylceramidase/GBA Antibody [H00002629-B01P]

Western Blot: Glucosylceramidase/GBA Antibody [H00002629-B01P] - Analysis of GBA expression in U-2 OS.
Western Blot: Glucosylceramidase/GBA Antibody [H00002629-B01P]

Western Blot: Glucosylceramidase/GBA Antibody [H00002629-B01P]

Western Blot: Glucosylceramidase/GBA Antibody [H00002629-B01P] - Analysis of GBA expression in transfected 293T cell line by GBA polyclonal antibody. Lane 1: GBA transfected lysate(58.96 KDa). Lane 2: Non-transfected lysate.

Applications for Glucosylceramidase/GBA Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against Recombinant Protein with GST tag by WB and also on transfected lysate in WB. GST tag alone is used as a negative control. IP usage reported by a customer review.

Reviewed Applications

Read 1 review rated 5 using H00002629-B01P in the following applications:

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Glucosylceramidase/GBA

This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq]

Alternate Names

Alglucerase, GBA, GBA1, Imiglucerase

Entrez Gene IDs

2629 (Human)

Gene Symbol

GBA

UniProt

AAH03356.1 (Human)

Additional Glucosylceramidase/GBA Products

Product Documents for Glucosylceramidase/GBA Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Glucosylceramidase/GBA Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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