GluR1 Antibody (RH95)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-29534

Novus Biologicals, part of Bio-Techne
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NBP2-29534
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Key Product Details

Species Reactivity

Validated:

Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # RH95

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all GluR1 Antibodies »

Product Summary for GluR1 Antibody (RH95)

Immunogen

Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH. Accession # P19490

Reactivity Notes

The antibody has been directly tested for reactivity in Western blots with mouse and rat tissue. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Specificity

Specific for endogenous levels of the ~105 kDa GluR1 protein.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Theoretical MW

100 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for GluR1 Antibody (RH95)

Western Blot: GluR1 Antibody (RH95) [NBP2-29534]

Western Blot: GluR1 Antibody (RH95) [NBP2-29534]

Western Blot: GluR1 Antibody (RH95) [NBP2-29534] - Rat hippocampal lysate showing specific immunolabeling of the ~105k GluR1 protein.

Applications for GluR1 Antibody (RH95)

Application
Recommended Usage

Western Blot

1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: GluR1

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinanen et al., 1990;Hollmann and Heinemann, 1994).

Long Name

Glutamate Receptor 1

Alternate Names

GluA1, GLURA, GRIA1

Entrez Gene IDs

50592 (Rat)

Gene Symbol

GRIA1

UniProt

P19490 (Rat)

Additional GluR1 Products

Product Documents for GluR1 Antibody (RH95)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GluR1 Antibody (RH95)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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