GluR1 [p Ser845] Antibody (SR1027)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21554

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21554-100ul
NBP3-21554-50ul
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1027

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all GluR1 Antibodies »

Product Summary for GluR1 [p Ser845] Antibody (SR1027)

Immunogen

A synthesized peptide derived from human phospho-GluR1 [Ser845] (Uniprot #: P42261)

Modification

p Ser 845

Specificity

Detects endogenous levels of phospho-GluR1 [Ser845]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

102 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for GluR1 [p Ser845] Antibody (SR1027)

Western Blot: GluR1 [p Ser 845] Antibody (SR1027) [NBP3-21554] -

Western Blot: GluR1 [p Ser 845] Antibody (SR1027) [NBP3-21554] - Western blot analysis using NBP3-21554 in (1) Human brain lysate treated with Lambda phosphatase lysate; (2) Human brain lysate.

Applications for GluR1 [p Ser845] Antibody (SR1027)

Application
Recommended Usage

Western Blot

1:500-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GluR1

Glutamate Receptor 1 belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for Glutamate Receptor 1. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists.

Long Name

Glutamate Receptor 1

Alternate Names

GluA1, GLURA, GRIA1

Gene Symbol

GRIA1

Additional GluR1 Products

Product Documents for GluR1 [p Ser845] Antibody (SR1027)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GluR1 [p Ser845] Antibody (SR1027)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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