GluR1 [p Ser845] Antibody
Novus Biologicals, part of Bio-Techne | Catalog # NB300-171
![Western Blot: GluR1 [p Ser845] Antibody [NB300-171]](https://resources.bio-techne.com/images/products/GluR1-%5Bp-Ser845%5D-Antibody-Western-Blot-NB300-171-img0003.jpg "Western Blot: GluR1 [p Ser845] Antibody [NB300-171]")
Key Product Details
Validated by
Biological Validation
Species Reactivity
Validated:
Mouse, Rat
Cited:
Mouse
Predicted:
Human (100%), Primate (100%). Backed by our 100% Guarantee.
Applications
Validated:
Immunohistochemistry, Immunohistochemistry-Frozen, Western Blot
Cited:
Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser845 conjugated to KLH. Accession # P19490
Reactivity Notes
Mouse reactivity reported in scientific literature (PMID: 24212670)
Modification
p Ser845
Localization
Cell Membrane
Specificity
Specific for endogenous levels of the ~100 kDa GluR1 protein phosphorylated at Ser845. Immunolabeling is completely eliminated by treatment with lambda-phosphatase.
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Theoretical MW
100 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Scientific Data Images for GluR1 [p Ser845] Antibody
![Western Blot: GluR1 [p Ser845] Antibody [NB300-171]](https://resources.bio-techne.com/images/products/GluR1-[p-Ser845]-Antibody-Western-Blot-NB300-171-img0003.jpg "Western Blot: GluR1 [p Ser845] Antibody [NB300-171]")
Western Blot: GluR1 [p Ser845] Antibody [NB300-171]
Western Blot: GluR1 [p Ser845] Antibody [NB300-171] - Rat hippocampal lysate showing specific immunolabeling of the ~100k GluR1 protein phosphorylated at Ser845 (Control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase: lambda-Ptase). The blot is identical to the control except that it was incubated in lambda-Ptase (1200 units for 30 min) before being exposed to the GluR1 Ser845 antibody. The immunolabeling is completely eliminated by treatment with lambda-Ptase.Applications for GluR1 [p Ser845] Antibody
Application
Recommended Usage
Immunohistochemistry
1:1000
Immunohistochemistry-Frozen
1:1000
Western Blot
1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
Preservative
No Preservative
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at -20C. Avoid freeze-thaw cycles.
Background: GluR1
Long Name
Glutamate Receptor 1
Alternate Names
GluA1, GLURA, GRIA1
Gene Symbol
GRIA1
UniProt
Additional GluR1 Products
Product Documents for GluR1 [p Ser845] Antibody
Product Specific Notices for GluR1 [p Ser845] Antibody
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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