Key Product Details

Species Reactivity

Validated:

Human, Rat, Primate

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Radioimmunoassay, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # 3A11

Format

Azide and BSA Free

Concentration

1.7 mg/ml

View all GluR2 Antibodies »

Product Summary for GluR2 Antibody (3A11) - Azide and BSA Free

Immunogen

Recombinant fusion protein TrpE-GluR2.

Specificity

Glutamate Receptor 2 (GluR2) by Western Blot and RIA. When using MAB396 for immunohistochemistry or immunoprecipitation it recognizes both GluR2 and GluR4.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Description

Relevant Entrez Gene Numbers: NM_000839.2

Scientific Data Images for GluR2 Antibody (3A11) - Azide and BSA Free

Immunocytochemistry/ Immunofluorescence: GluR2 Antibody (3A11) - Azide and BSA Free [NBP2-29731]

Immunocytochemistry/ Immunofluorescence: GluR2 Antibody (3A11) - Azide and BSA Free [NBP2-29731]

Immunocytochemistry/Immunofluorescence: GluR2 Antibody (3A11) - Azide and BSA Free [NBP2-29731] - Mouse anti-GluR staining of adult monkey pryamidal cells.

Applications for GluR2 Antibody (3A11) - Azide and BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

1:10-1:500

Immunohistochemistry

1:500-1000

Immunoprecipitation

1:10-1:500

Radioimmunoassay

1:100-1:2000

Western Blot

1:100-1:2000
Application Notes
Immunohistochemistry on 4% paraformaldehyde fixed tissue.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1.7 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: GluR2

The GRIA2 gene encodes for glutamate receptor 2 with an isoform flop of 883 amino acids, 98 kDA, isoform flip of 883 amino acids and 98 kDA, and an isoform 3 of 901 amino acids long and 100 kDA. Glutamate receptors function as a ligand-gated ion channel in the central nervous system and are the predominant excitatory neurotransmitter receptors in the brain. GRIA2 has been researched regarding its role in Alzheimer's disease, multiple sclerosis, motor neuron disease, epilepsy, anorexia, bioplar disorder, and neurodegeneration. GRIA2 is involved in the CREB pathway, intracellular calcium signaling, glutamic acid signaling, and calcium channels as well as interacts with genes NSF, GRIA3, DLG4, GRID2, and SDCBP.

Long Name

Glutamate Receptor 2

Alternate Names

AMPA2, GluA2, GluR-K2, GLURB, GRIA2, HBGR2

Gene Symbol

GRIA2

UniProt

Q14416

Additional GluR2 Products

Product Documents for GluR2 Antibody (3A11) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for GluR2 Antibody (3A11) - Azide and BSA Free

Relevant Entrez Gene Numbers: NM_000839.2

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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