Glutaredoxin 3/GLRX3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-20767

Novus Biologicals, part of Bio-Techne
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NBP2-20767
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Glutaredoxin 3/GLRX3 Antibodies »

Product Summary for Glutaredoxin 3/GLRX3 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human Glutaredoxin 3/GLRX3. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Xenopus laevis (80%).

Localization

Cytoplasm; cell cortex

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

37 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Glutaredoxin 3/GLRX3 Antibody

Western Blot: Glutaredoxin 3/GLRX3 Antibody [NBP2-20767]

Western Blot: Glutaredoxin 3/GLRX3 Antibody [NBP2-20767]

Western Blot: Glutaredoxin 3/GLRX3 Antibody [NBP2-20767] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 10% SDS PAGE gel, diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: Glutaredoxin 3/GLRX3 Antibody [NBP2-20767]

Immunocytochemistry/ Immunofluorescence: Glutaredoxin 3/GLRX3 Antibody [NBP2-20767]

Immunocytochemistry/Immunofluorescence: Glutaredoxin 3/GLRX3 Antibody [NBP2-20767] - Analysis of methanol-fixed A431, using antibody at 1:200 dilution.
Immunohistochemistry-Paraffin: Glutaredoxin 3/GLRX3 Antibody [NBP2-20767]

Immunohistochemistry-Paraffin: Glutaredoxin 3/GLRX3 Antibody [NBP2-20767]

Immunohistochemistry-Paraffin: Glutaredoxin 3/GLRX3 Antibody [NBP2-20767] - Human breast carcinoma. TXNL2 antibody [N2C3] dilution: 1:200. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.
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Applications for Glutaredoxin 3/GLRX3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Immunoprecipitation

1:100-1:500

Western Blot

1:1000-1:10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Glutaredoxin 3/GLRX3

This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq]

Alternate Names

GLRX3, GLRX4, GRX3, GRX4, PICOT, TXNL2

Gene Symbol

GLRX3

UniProt

O76003 (Human)

Additional Glutaredoxin 3/GLRX3 Products

Product Documents for Glutaredoxin 3/GLRX3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Glutaredoxin 3/GLRX3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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