Glutathione Peroxidase 2/GPX2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1888

Novus Biologicals, part of Bio-Techne
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NB100-1888
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human, Mouse, Rat

Predicted:

Bovine (100%), Canine (100%), Porcine (100%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Western Blot

Cited:

IF/IHC, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Glutathione Peroxidase 2/GPX2 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-SLDGEKVDFN corresponding to internal region according to NP_002074.2.

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 19151108); Rat reactivity reported in scientific literature (PMID: 18056462).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Glutathione Peroxidase 2/GPX2 Antibody

Western Blot: Glutathione Peroxidase 2/GPX2 Antibody [NB100-1888]

Western Blot: Glutathione Peroxidase 2/GPX2 Antibody [NB100-1888]

Western Blot: Glutathione Peroxidase 2/GPX2 Antibody [NB100-1888] - Staining (0.5ug/ml) of Human Liver lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.

Applications for Glutathione Peroxidase 2/GPX2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10 - 1:500

Peptide ELISA

Detection limit 1:32000

Western Blot

0.5 - 2 ug/ml
Application Notes
WB: Approx. 24 kDa band observed in human liver lysates (calculated MW of 21.9 kDa band according to NP_002074.2). Use in IHC-P reactivity reported in (PMID: 24562575).
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Glutathione Peroxidase 2/GPX2

This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract.

Alternate Names

GIGPX, GPRP, GPX2

Entrez Gene IDs

2877 (Human); 14776 (Mouse); 29326 (Rat)

Gene Symbol

GPX2

UniProt

NP_002074.2. (Human)

Additional Glutathione Peroxidase 2/GPX2 Products

Product Documents for Glutathione Peroxidase 2/GPX2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Glutathione Peroxidase 2/GPX2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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