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Glutathione S-Transferase mu 1/GSTM1 Antibody (1H4F2) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-22186

Novus Biologicals, part of Bio-Techne
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NBP2-22186
NBP2-22186-0.025ml

Key Product Details

Species Reactivity

Validated:

Human, Rat

Cited:

Human, Rat

Applications

Validated:

ELISA, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 1H4F2

Format

BSA Free

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Product Specifications

Immunogen

Purified recombinant fragment of human Glutathione S-Transferase mu 1/GSTM1 expressed in E. Coli.

Localization

Cytoplasm

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

26 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Glutathione S-Transferase mu 1/GSTM1 Antibody (1H4F2) - BSA Free

Western Blot: Glutathione S-Transferase mu 1/GSTM1 Antibody (1H4F2)BSA Free [NBP2-22186]

Western Blot: Glutathione S-Transferase mu 1/GSTM1 Antibody (1H4F2)BSA Free [NBP2-22186]

Western Blot: Glutathione S-Transferase mu 1/GSTM1 Antibody (1H4F2) [NBP2-22186] - Western blot analysis using GSTM1 mouse mAb against MCF-7 (1), PC-12 (2), Jurkat (3), Hela (4), HL7702 (5) and HepG2 (6) cell lysate.
Immunohistochemistry-Paraffin: Glutathione S-Transferase mu 1/GSTM1 Antibody (1H4F2) - BSA Free [NBP2-22186]

Immunohistochemistry-Paraffin: Glutathione S-Transferase mu 1/GSTM1 Antibody (1H4F2) - BSA Free [NBP2-22186]

Immunohistochemistry-Paraffin: Glutathione S-Transferase mu 1/GSTM1 Antibody (1H4F2) [NBP2-22186] - Analysis of stomach cancer tissues using GSTM1 mouse mAb with DAB staining.
Flow Cytometry: Glutathione S-Transferase mu 1/GSTM1 Antibody (1H4F2) - BSA Free [NBP2-22186]

Flow Cytometry: Glutathione S-Transferase mu 1/GSTM1 Antibody (1H4F2) - BSA Free [NBP2-22186]

Flow Cytometry: Glutathione S-Transferase mu 1/GSTM1 Antibody (1H4F2) [NBP2-22186] - Flow cytometric analysis of Hela cells using GSTM1 mouse mAb (green) and negative control (red).

Applications for Glutathione S-Transferase mu 1/GSTM1 Antibody (1H4F2) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Flow Cytometry

1:200-1:400

Immunohistochemistry

1:200 - 1:1000

Immunohistochemistry-Paraffin

1:200-1:1000

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Ascites

Format

BSA Free

Preservative

0.03% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Glutathione S-Transferase mu 1/GSTM1

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.

Alternate Names

Glutathione STransferase mu 1, GST1, GSTM1, GTH4, GTM1

Gene Symbol

GSTM1

Additional Glutathione S-Transferase mu 1/GSTM1 Products

Product Documents for Glutathione S-Transferase mu 1/GSTM1 Antibody (1H4F2) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Glutathione S-Transferase mu 1/GSTM1 Antibody (1H4F2) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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